What Cause Of Polycystic Kidney Disease(pkd)

What Cause Of Polycystic Kidney Disease(pkd)Polycystic kidney disease is a kidney disorder passed down through families in which many cysts form in the kidneys, causing them to become enlarged.

There are two types of polycystic kidney disease, caused by different genetic flaws:

Autosomal dominant polycystic kidney disease (ADPKD). Signs and symptoms of ADPKD often develop between the ages of 30 and 40. In the past, this type was called adult polycystic kidney disease, but children can develop the disorder. Only one parent needs to have the disease in order for it to pass along to the children. If one parent has ADPKD, each child has a 50 percent chance of getting the disease. This form accounts for about 90 percent of cases of polycystic kidney disease.

Autosomal recessive polycystic kidney disease (ARPKD). This type is far less common than is ADPKD. The signs and symptoms often appear shortly after birth. Sometimes, symptoms don’t appear until later in childhood or during adolescence. Both parents must have abnormal genes to pass on this form of the disease. If both parents carry a gene for this disorder, each child has a 25 percent chance of getting the disease.

PKD is associated with the following conditions:

Aortic aneurysms

Brain aneurysms

Cysts in the liver, pancreas, and testes

Diverticula of the colon

As many as half of people with PKD have cysts on the liver. A family history of PKD increases your risk for the condition.

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